Peripheral Metabolism of Hormones: Clinical Implications
نویسندگان
چکیده
منابع مشابه
Peripheral metabolism of thyroid hormones: a review.
Peripheral metabolism of thyroid hormones is a critical component of the impact these hormones have on intracellular function. Thyroid hormones can be metabolized in peripheral tissue by deiodination, conjugation, deamination, and decarboxylation enzyme reactions. Therefore, alterations in these metabolic pathways might significantly impact the quantity of specific thyroid hormone metabolites i...
متن کاملchemistry, metabolism, and toxicology of cannabis: clinical implications.
cannabis is one of the most widely abused substances throughout the world. the primary psychoactive constituent of cannabis, delta 9-tetrahydrocannabinol (▵(9_)thc), produces a myriad of pharmacological effects in animals and humans. although it is used as a recreational drug, it can potentially lead to dependence and behavioral disturbances and its heavy use may increase the risk for psychotic...
متن کاملPeripheral Regulation of Energy Metabolism by Thyroid Hormones
Thyroid hormone is long known as an important regulator of metabolism. It exerts general effects such as increased cycling of metabolites and stimulation of ATP turnover in spite of reduced efficiency of oxidative phosphorylation, but also very specific effects in peripheral tissues. This article reviews the most relevant metabolic effects of thyroid hormone in peripheral tissues, including the...
متن کاملClinical implications of the organizational and activational effects of hormones.
Debate on the relative contributions of nature and nurture to an individual's gender patterns, sexual orientation and gender identity are reviewed as they appeared to this observer starting from the middle of the last century. Particular attention is given to the organization-activation theory in comparison to what might be called a theory of psychosexual neutrality at birth or rearing consiste...
متن کاملMetabolism of the Steroid Hormones
The biological relationship between ac-estradiol and estrone has been established by the isolation of the latter compound from the urine of normal and ovariectomized female and normal male guinea pigs (2, 3) and man (4,5) following the administration of cu-estradiol. In view of the conclusion of Pincus (6), that a-estradiol is not converted to estrone by the ovariectomized rabbit, it was consid...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1979
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107687907200603